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Saturday, February 4, 2023

Fresh Hope For Anti-ageing Drug As Lifespans Could Be Lengthened With Technique Used On Mice 

Researchers believe lifespan could be extended by anti-aging drugs within five years.

Humans may soon be tested with a similar technique used to extend the lifespan of mice.

This landmark study shows how the reprogramming of cells used to rejuvenate cells in a dish could translate into a therapy.

The goal is to create a drug to increase resistance to diseases such as cancer and Dementiaand make people biologically younger.

Anti-aging drugs could extend lifespan within five years, researchers believe (stock image)

“We could easily see something in humans with this technology within the next five years,” said Dr Noah Davidson, chief scientist at Rejuvenate Bio, the company behind the study.

Dr Ildem Akerman, Associate Professor of Functional Genomics at the University of Birmingham, added: “Reversing aging in an entire animal using genetic programming has never been achieved before.”

Researchers injected mice with a human age in their seventies with a modified virus carrying an extra segment of genetic code, era report.

It allows the rodent’s cells to produce Yamanaka factors, a group of proteins that have been used since the mid-2000s to induce cells to revert to a “younger” embryonic state.

The treated mice lived an additional 18 weeks, compared with 9 weeks for untreated mice.

The treatment group also restored the epigenetic pattern typical of young animals.

The study, posted on biorxiv.org, has not yet been peer-reviewed.

The ONS predicts that men born in the UK in 2070 will expect to live to an average of 85 years, while women will be closer to 88 when they die

The ONS predicts that men born in the UK in 2070 will expect to live to an average of 85 years, while women will be closer to 88 when they die

Dr Andrew Steele, a British computational biologist and author of a new book on longevity, previously told MailOnline There’s No Biological Reason Humans Don’t Live Before 200.

He believes the big breakthrough will come in the form of drugs that remove the body’s “zombie cells,” thought to be one of the culprits in the decay of tissues and organs with age.

Pills to flush these cells out of the body are already in human trials and could be on the market in as little as 10 years, Dr Steele said, and he believes someone reading this could live to 150 with the drug’s help.

Another area of ​​particular interest to antiaging scientists is the study of DNA from reptiles and other cold-blooded animals.

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